Imukin is a specific interferon used to prevent infections in people with a condition called chronic granulomatous disease. Imukin is also used to treat a congenital bone disorder called osteopetrosis.
Imukin is used with other treatments to reduce the frequency of serious infections in people with CGD.
The following adverse reactions are described below and elsewhere in the warnings and precautions section of the labeling:
Bone Marrow Toxicity
Imukin is an injection and each vial contains 2 million International Units (IU) or 100 micrograms of interferon gamma-1b (recombinant) in 0.5 mL of solution. The solution also contains mannitol, sodium succinate, succinic acid, polysorbate 20 and water for injections.
How to use
Injections are usually administered under the skin three times a week (for example, Monday, Wednesday, Friday) and can be given by a doctor, nurse, family member or by the patient who can be trained in giving the injections correctly. This should be injected immediately after it is withdrawn from the vial and any unused portion of the vial should be thrown away. Keep using it until your doctor tells you to stop.
Important Administration Instructions
The optimum sites of subcutaneous injection are the right and left deltoid and anterior thigh.
This drugs can be administered by a physician, nurse, family member or patient when appropriately counseled in the administration of subcutaneous injections.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. It is a clear, colorless solution.
Its is for a single use only. Discard any unused portion. Imukin does not contain a preservative.
Imukin should not be mixed with other drugs in the same syringe.
Administer Imukin using either sterilized glass or plastic disposable syringes.