IFA Diety AP 20mg is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. However, due to an addictive potential, it is listed as an illicit substance in many countries. Structurally, IFA Diety AP 20mg (N-2-cyanoethylamphetamine) falls within the phenylethamine and amphetamine chemical class of drugs.
IFA Diety AP 20mg is an amphetamine based anorectic which is rapidly metabolized into amphetamine in the body.
Dosage IFA Diety AP
The initial dose is 10 mg / day. With lack of effectiveness when used in this dose (weight loss less than 2 kg for 4 weeks) and if tolerated the dose can be increased to 15 mg / day.
If no effect when Ifa Diety Getz Pharma used in doses of 15 mg / day (weight loss less than 2 kg per 4 weeks), this drug should be discontinued.
In patients not adequately responding to treatment, that is who within 3 months can not reach the level of 5% weight loss from baseline, the duration of use this medication should not exceed 3 months.
The course of treatment is not more than 1 year since no data on efficacy and safety of longer use.
Do not use sibutramine, if after made weight loss achieved in the course of further therapy, the patient again adds to the weight of 3 kg or more.
Side effects IFA Diety AP 20mg
Digestive system: frequently – anorexia, constipation, dry mouth, nausea, transient increases in liver enzymes.
CNS and peripheral nervous system: insomnia, headaches, dizziness, anxiety, paresthesia, increased sweating, change in taste, seizures; one patient with schizoaffective disorder, which presumably existed prior to initiating therapy with sibutramine after treatment developed acute psychosis.
Cardiovascular system: tachycardia, palpitations, increased blood pressure (moderate rise of blood pressure at rest of 1-3 mm Hg and a moderate increase in heart rate by 3-7 beats / min), vasodilation (flushing with a sensation of heat), exacerbation of hemorrhoids; in some cases – a more pronounced increase in blood pressure and heart rate acceleration.
Urinary system: in rare cases – acute interstitial nephritis, mesangiocapillary glomerulonephritis.
Blood coagulation system: thrombocytopenia, Henoch-Schonlein purpura.
Most often side effects occur early in therapy (the first 4 weeks), their severity and frequency of occurrence over time are weaken.
IFA Diety AP 20mg Interactions
When this IFA Diety AP 20mg applied simultaneously with:
– drugs inhibiting isoenzyme CYP3A4 (ketoconazole, erythromycin, troleandomycin, cyclosporine) increased plasma concentrations of metabolites of sibutramine, slightly increased the interval of QT.
– rifampin, phenytoin, carbamazepine, phenobarbital, dexamethasone, macrolide antibiotics may accelerate the metabolism of this medication.
– selective serotonin reuptake inhibitors (citalopram, fluoxetine, paroxetine, sertraline), agonist 5-HT1-receptors, derivatives of ergot alkaloids, opioids, centrally acting antitussives increases the risk of serotonin syndrome. You may need another drug like Acxion Fentermina.