Giotrif 40mg (Afatinib) is used to treat a certain type of lung cancer(non-small cell lung cancer) that has spread to other parts of the body. It belongs to a class of drugs known as kinase inhibitors.
Giotrif 40mg (Afatinib) works by slowing or stopping the growth of cancer cells. It binds to a certain protein (epidermal growth factor receptor-EGFR) in some tumors.Afatinib is also used to treat squamous non-small cell lung cancer that has spread to other parts of the body after other cancer medicine has been tried without successful treatment.
How Giotrif 40mg Is Given
Giotrif 40mg (Afatinib) is a pill, taken by mouth.
Take afatinib on an empty stomach at least 1 hour before or 2 hours after a meal.
Take afatinib exactly as prescribed.
Swallow afatinib tablets whole with at least 8 ounces of water. Do not crush or dissolve tablets.
Do not change your dose or stop afatinib unless your health care provider tells you to.
If you miss a dose and your next dose is due in: Less than 12 hours, take your next dose at the normal time. Do not make up the next dose.
12 hours or more, take the missed dose as soon as you remember. Take your next dose at the normal time.
Do not take more than 1 dose of afatinib at one time. Call your health care provider and go to the emergency room right away if you take too much.
Store at room temperature (68° F to 77° F); keep medication in original bottle; protect from high humidity, moisture and light.
Keep out of reach from children and pets.
Safely throw away any afatinib that is out of date or unused (ask your provider for directions on how to discard the medication).
The amount of afatinib that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition you have.
Side Effects Giotrif 40mg
Important things to remember about the side effects of Giotrif 40mg 40mg (Afatinib):
Most people will not experience all of the afatinib side effects listed.
Afatinib side effects are often predictable in terms of their onset, duration, and severity.
Afatinib side effects are almost always reversible and will go away after therapy is complete.
Afatinib side effects may be quite manageable. There are many options to minimize or prevent the side effects of afatinib.
The following side effects are common (occurring in greater than 30%) for patients taking afatinib :
Acneiform eruption (group of skin conditions resembling acne)
Paronychia (infection of nails)
These are less common side effects (occurring in 10-29%) for patients receiving afatinib:
Cystitis (bladder infection)
Cheilitis (inflammation of the lips)
Hypokalemia (low potassium)
Conjunctivitis (pink eye)
Rhinorrhea (runny nose)
Elevated liver enzymes
Not all side effects are listed above. Some that are rare (occurring in less than about 10 percent of patients) are not listed here. Always inform your health care provider if you experience any unusual symptoms.
Giotrif 40mg (Afatinib) Precautions
Before starting afatinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
While taking afatinib, do not receive any kind of immunization or vaccination without your doctor’s approval.
Limit your time in the sun. Afatinib can make your skin sensitive to sunlight. A severe sunburn, rash or worsening acne can occur with too much exposure. Remember to use sunscreen and wear a hat and clothes that cover as much of your skin as possible while taking afatinib.
Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D (may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus.)
For both men and women: Barrier methods of contraception, such as condoms, are recommended during therapy and for at least 2 weeks after treatment is complete. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.
Do not breast feed while taking afatinib. Contact us if you need more information