Esbelcaps 20mg/6mg (Fenproporex and Diazepam) Capsules


Esbelcaps 20mg/6mg (Fenproporex and Diazepam) is a benzodiazepine derivative tranquilizer. It provides anxiolytic, sedative, anticonvulsant, central muscle relaxant effect.

Name: Esbelcaps

Packing: 30 Capsules pack

Form: Capsules



Esbelcaps 20mg/6mg (Fenproporex and Diazepam) is a benzodiazepine derivative tranquilizer. It provides anxiolytic, sedative, anticonvulsant, central muscle relaxant effect. The mechanism of action is associated with increased inhibitory effect of GABA in the CNS. Muscle relaxant effect is also due to the inhibition of spinal reflexes. This medication may cause anticholinergic effects.

Why is Esbelcaps 20mg/6mg (Fenproporex and Diazepam) prescribed?

neuroses, borderline states with symptoms of stress, restlessness, anxiety, fear
sleep disturbance, motor stimulation of various etiologies in neurology and psychiatry, withdrawal syndrome in chronic alcoholism
spastic conditions associated with lesions of the brain or spinal cord, and myositis, bursitis, arthritis, accompanied by a voltage of skeletal muscle
status epilepticus
premedication before anesthesia as a component of combined anesthesia
relief labor, premature birth, abruptio placenta, tetanus

Esbelcaps 20mg/6mg (Fenproporex and Diazepam) drug interactions

When used Esbelcaps 20mg/6mg (Fenproporex and Diazepam) with drugs providing a depressing effect on the CNS (including with antipsychotics, sedatives, hypnotics, opioid analgesics, drugs for anesthesia), enhanced inhibitory effect on the central nervous system, the respiratory center, pronounced arterial hypotension.

When used Esbelcaps 20mg/6mg (Fenproporex and Diazepam) with the tricyclic antidepressants (including amitriptyline) may be increasing of the CNS depressant effect, increasing concentrations of antidepressants and increased cholinergic action.

Patients receiving long-term antihypertensive medications central action, beta-blockers, anticoagulants, cardiac glycosides, the extent and mechanisms of drug interactions are unpredictable.

Simultaneous administration with muscle relaxants the action of muscle relaxants increases, also increases the risk of apnea.

Co-administration with oral contraceptives may increase the effects of this drug. The risk of breakthrough bleeding increases.

Simultaneous administration with bupivacaine may increase the concentration of bupivacaine in blood plasma; with diclofenac – may increase dizziness; with isoniazid – a decrease of Esbelcaps (Diazepam) elimination from the body.

Drugs that cause induction of liver enzymes, including antiepileptic drugs (carbamazepine, phenytoin) may accelerate the elimination of Esbelcaps 20mg/6mg (Fenproporex and Diazepam).

When this medicine used with caffeine decreases sedative and possibly anxiolytic action of this drug.

Simultaneous administration with with clozapine may be expressed as hypotension, respiratory depression, loss of consciousness; with levodopa – may suppress antiparkinsonian action; with lithium carbonate – described a case of coma, with metoprolol – possible decreased visual acuity, impairment of psychomotor reactions.

Simultaneous administration with paracetamol may decrease excretion of Esbelcaps (Diazepam) and its metabolite desmethyldiazepam; with risperidone – described the cases of NMS.

Co-administration with rifampicin increased excretion of this drug is due to a significant increase in its metabolism under the influence of rifampicin.

Theophylline at low doses changes a sedative effect of this drug.

In rare cases Esbelcaps (Diazepam) inhibits the metabolism and increases the effect of phenytoin. Phenobarbital and phenytoin may accelerate the metabolism of Esbelcaps (Diazepam).

Fluvoxamine increases plasma concentrations and side effects of Esbelcaps (Diazepam).

Cimetidine, omeprazole, disulfiram may increase the intensity and duration of action of Esbelcaps (Diazepam).

Alcohol and alcohol containing drugs enhanced inhibitory effect on the central nervous system (mainly on the respiratory center) but can also occur syndrome of pathological intoxication. You may need other weight loss pills

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