Dexedrine 5mg (dextroamphetamine) is an amphetamine medication used to treat ADHD via a long- or short-acting capsule. Here, get essential treatment information about uses, side effects, dosages, potential for abuse, and more.
Dexedrine 5mg (dextroamphetamine) works in the treatment of ADHD by increasing attention and decreasing restlessness in children and adults who are overactive, cannot concentrate for very long, or are easily distracted and impulsive. Dexedrine is used as part of a total treatment program that also includes social, educational, and psychological treatment.
Dosage and Administration
Amphetamines should be administered at the lowest effective dosage and dosage should be individually adjusted. Late evening doses should be avoided because of the resulting insomnia.
Usual dose is 5 to 60 mg per day in divided doses, depending on the individual patient response. Narcolepsy seldom occurs in children under 12 years of age; however, when it does, DEXEDRINE may be used. The suggested initial dose for patients aged 6 to 12 is 5 mg daily; daily dose may be raised in increments of 5 mg at weekly intervals until an optimal response is obtained. In patients 12 years of age and older, start with 10 mg daily; daily dosage may be raised in increments of 10 mg at weekly intervals until an optimal response is obtained. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced. Dexedrine 5mg (dextroamphetamine) may be used for once-a-day dosage wherever appropriate.
Attention Deficit Disorder With Hyperactivity
The drug is not recommended for pediatric patients younger than 6 years of age.
In pediatric patients 6 years of age and older, start with 5 mg once or twice daily; daily dosage may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day. Dexedrine 5mg (dextroamphetamine) may be used for once-a-day dosage wherever appropriate. Where possible, drug administration should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy.
Side Effects Dexedrine 5mg
Palpitations, tachycardia, elevation of blood pressure. There have been isolated reports of cardiomyopathy associated with chronic amphetamine use.
Central Nervous System
Psychotic episodes at recommended doses (rare), overstimulation, restlessness, dizziness, insomnia, euphoria, dyskinesia, dysphoria, tremor, headache, exacerbation of motor and phonic tics, and Tourette’s syndrome.
Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. Anorexia and weight loss may occur as undesirable effects.
Impotence, changes in libido, frequent or prolonged erections.
Skin and Subcutaneous Tissue Disorders
Drug Abuse And Dependence
Dextroamphetamine sulfate is a Schedule II controlled substance. Amphetamines have been extensively abused. Tolerance, extreme psychological dependence and severe social disability have occurred. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with amphetamines include severe dermatoses, marked insomnia, irritability, hyperactivity, and personality changes. The most severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.
Dexedrine 5mg (dextroamphetamine) Interactions
Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking before taking dextroamphetamine, especially:
Alpha blockers such as Uroxatral (alfuzosin (Uroxatral), Cardura (doxazosin), Minipress (prazosin), Flomax (tamsulosin), and Hytrin (terazosin)
Antacids and other medications for heartburn or peptic ulcers
Antidepressants such as Norpramin (desipramine) and Vivactil (protriptyline)
Antihistamines (medications for colds and allergies)
Arm and Hammer Baking Soda or Soda Mint (sodium bicarbonate)
Ascorbic acid (Vitamin C)
Beta blockers such as Tenormin (atenolol), Normodyne (labetalol), Corgard (nadolol), Inderal (propranolol), and Lopressor or Toprol XL (metoprolol)
Darvon or Darvon-N (propoxyphene)
Diuretics (water pills)
Hiprex or Urex (methenamine)
Lithobid and Eskalith (lithium)
Medications for high blood pressure
Medications for seizures such as Zarontin (ethosuximide), Dilantin (phenytoin), and Luminal or Solfoton (phenobarbital)
Supplements that contain glutamic acid (L-glutamine)
Make sure you also tell your doctor if you’re taking a monoamine oxidase inhibitor (MAOI) or have stopped taking one in the past two weeks.
Eldepryl, Emsam, or Zelapar (selegiline)
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