Dexedrine 15mg (dextroamphetamine) is used to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy (uncontrollable desire for sleep or a sudden attack of deep sleep). Dexedrine 15mg (dextroamphetamine) belongs to the group of medicines called central nervous system (CNS) stimulants.
Dexedrine 15mg (dextroamphetamine) interactions
Acidifying agents – Gastrointestinal acidifying agents (guanethidine,reserpine, glutamic acid HCl,ascorbic acid, fruit juices, etc.) lower absorption of amphetamines Urinary acidifying agents -(ammonium chloride, sodium acid phosphate, etc.) Increase the concentration of the ionized species of the Dexedrine Primary excretion – Both Groups of agents lower blood levels and efficacy of amphetamines Adrenergic blockers – Adrenergic blockers are inhibited by amphetamines Alkalinizing agents -Gastrointestinal alkalinizing agents (sodium bicarbonate, etc.)increase absorption of amphetamines. Urinary alkalinizing agents (acetazolamide, some thiazides) increase the concentration of the non-ionized species of the Dexedrine 15mg (dextroamphetamine) molecule, thereby decreasing urinary excretion. Both groups of agents increase blood levels and therefore potentate the actions of amphetamines Antidepressants, tricyclic – Ferndexs may enhance the activity of tricyclic or sympathomimetic agents; d-Dexedrine with desipramine or protriptyline and possibly other tricyclics cause striking and sustained increases in the concentration of d-Dexedrine in the brain; cardiovascular effects can be potentiated MAO inhibitors – MAO antidepressants, as well as a metabolite of furazolidone, slow Dexedrine metabolism. This slowing potentiates amphetamines, increasing their effect on the release of norepinephrine and other monoamines from adrenergic nerve endings, this can cause headaches and other signs of hypertensive crisis. A variety of neurological toxic effects and malignant hyperpyrexia can occur, sometimes with fatal results Antihistamines – Ferndexs may counteract the sedative effect of antihistamines Antihypertensives – Ferndexs may antagonize the hypotensive effects of antihypertensives Chlorpromazine – Chlorpromazine blocks dopamine and norepinephrine receptors, thus inhibiting the central stimulant effects of amphetamines, and can be used to treat Dexedrine poisoning Ethosuximide – Ferndexs may delay intestinal absorption of ethosuximide Haloperidol – Haloperidol blocks dopamine receptors, thus inhibiting the central stimulant effects of amphetamines Lithium carbonate – The anorectic and stimulatory effects of amphetamines may be inhibited by lithium carbonate Meperidine – Ferndexs pone the analgesic effect of meperidine Methenamine therapy – Urinary excretion of amphetamines is increased, and efficacy is reduced, by acidifying agents used in methenamine therapy Norepinephrine – Ferndexs enhance the adrenergic effect of norepinephrine Phenobarbital – Ferndexs may delay intestinal absorption of phenobarbital; co-administration of phenobarbital may produce a synergistic anticonvulsant action Phenytoin – Ferndexs may delay intestinal absorption of phenytoin; co-administration of phenytoin may produce a synergistic anticonvulsant action Propoxyphene – In cases of propoxyphene overdose, Dexedrine 15mg (dextroamphetamine) CNS stimulation is potentiated and fatal convulsions can occur Veratrum alkaloids – Ferndexs inhibit the hypotensive effect of veratrum alkaloids Drug/Laboratory Test Interaction Ferndexs can cause a significant elevation in plasma corticosteroid levels. This increase is greatest in the evening Ferndexs may interfere with urinary steroid determinations.
Advanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma.
Patients with a history of drug abuse.
During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crisis may result).
Before using Dexedrine 15mg (dextroamphetamine) Elixir, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
Avoid caffeinated foods or drinks
Do not drive or operate machinery
Pregnant, planning to get pregnant or breastfeeding
Use sunscreen or wear protective clothing for sun protection. You may need Dexedrine 5mg also.