Desoxyn 5mg (Methamphetamine Hcl) is used to treat attention deficit hyperactivity disorder (ADHD). It is also to treat obesity in people who have not lost weight with diets or other treatments.
Desoxyn 5mg (Methamphetamine Hcl) is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.
What may interact with Desoxyn 5mg?
Do not take this medicine with any of the following medications:
• MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
• other stimulant medicines for attention disorders, weight loss, or to stay awake
This medicine may also interact with the following medications:
• certain medicines for blood pressure
• certain medicines for depression, anxiety, or psychotic disturbances
• certain medicines for diabetes
• cold or allergy medicines
• phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Dosage and Indications
For treatment of attention-deficit hyperactivity disorder (ADHD) characterized by moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Initially, 5 mg PO once or twice daily. May increase by increments of 5 mg at weekly intervals. Usual effective dose is 20 to 25 mg PO daily divided into 2 doses. Prescribe the lowest effective dose and, if possible, occasionally interrupt drug administration to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy. Use as part of a total treatment program that typically includes psychological, educational, and social remedial measures. Methylphenidate is usually not indicated if distractibility, short attention span, hyperactivity, emotional lability, and impulsivity are associated with acute stress reactions.
Children and Adolescents 6 years and older
Initially, 5 mg PO once or twice daily. Increase by increments of 5 mg at weekly intervals. Usual effective dose is 20 to 25 mg PO daily divided into 2 doses. Prescribe the lowest effective dose and, if possible, occasionally interrupt drug administration to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy. Use as part of a total treatment program that typically includes psychological, educational, and social remedial measures. Methylphenidate is usually not indicated if distractibility, short attention span, hyperactivity, emotional lability, and impulsivity are associated with acute stress reactions.
For the short-term (i.e., a few weeks) treatment of exogenous obesity in patients refractory to alternatives (e.g., repeated diets, group programs, and other drugs).
Adults, Adolescents, and Children 12 years and older
5 mg PO given 30 minutes before each meal. Methamphetamine is to be used with calorie restriction for only a few weeks, as tolerance to the anorectic effect usually develops within a few weeks. Discontinue methamphetamine once tolerance occurs; do NOT exceed the recommended dose in an attempt to increase the effect. The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. The total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. According to the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, short-term pharmacotherapy, such as with the amphetamine anorectics, has not been shown to produce longer-term health benefits in obese and overweight patients and cannot be generally recommended. Methamphetamine should not be used for long-term weight management; tolerance to the anorectic effect of the drug usually occurs within a few weeks.
For the treatment of narcolepsy†.
In one study, 20 mg PO in the morning within 1 hour of awakening to 8 patients with narcolepsy increased the time to fall asleep during a daytime nap opportunity from 4.53 +/- 3.41 minutes at baseline to 7.75 +/- 4.82 minutes; the mean time to fall asleep was 9.27 +/- 4.65 minutes after a dose of 40 to 60 mg. Among 8 patients without narcolepsy, the mean sleep latency time was 12.25 +/- 4.22 minutes. Improvements in driving skill were noted on driving simulator testing. In the study, methamphetamine was given daily for 4 days.
Side effects Desoxyn 5mg (Methamphetamine Hcl)
The most common side effects of Desoxyn 5mg (Methamphetamine Hcl) are as follows: fast heart beat, tremors, trouble sleeping, upset stomach, dry mouth, decreased appetite, headache, dizziness, and weight loss.
Other serious side effects include slowed growth in children, seizures, eyesight changes, and new or exacerbated heart and mental problems. Taking Desoxyn 5mg (Methamphetamine Hcl) may impair your or your teenager’s ability to drive, operate machinery, or perform other potentially dangerous tasks. This side effect usually wears off with time. If side effects are bothersome, or do not go away, talk to your doctor.
Most people taking this medication do not experience any of these side effects.
Report to your doctor any heart-related problems or a family history of heart and blood pressure problems. Patients with structural cardiac abnormalities and other serious heart problems have experienced sudden death, stroke, and heart attack while taking Desoxyn. Stimulants can increase blood pressure and heart rate. Physicians should monitor these vital signs closely during treatment. Call your doctor immediately if you or your child experiences warning signs such as chest pain, shortness of breath, or fainting while taking Desoxyn.
Also, disclose to your physician all mental health issues including any family history of suicide, bipolar illness, tics/Tourette’s syndrome, or depression. Desoxyn may create new or exacerbate existing behavior or mental problems, bipolar illness, or psychotic symptoms including but not limited to hearing voices, believing things that aren’t true, or manic symptoms. Call your doctor immediately if you or your child experiences new or worsening mental health symptoms including hallucinations or sudden suspicions.
Discuss circulation problems with your doctor before taking Desoxyn, which has been known to cause numbness, coolness, or pain in fingers or toes, including Raynaud’s phenomenon. Report to your doctor any new blood-flow problems, pain, skin color changes, or sensitivities to temperature while taking Desoxyn.